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Kelty backpack. Solid, serviceable, and in no hurry to fail.
Recently seen around $279.95 — check Amazon for the current price
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Kelty Trekker 65 Backpack Garnet, built for frequent travel.
Kelty helped establish the modern internal-frame pack and still builds around load transfer to the hips.
Currently $279.95. The case for it is simple: buy the version that lasts and stop thinking about it.